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  • Bacteriostatic vs Bactericidal Antibiotics

Bacteriostatic vs Bactericidal Antibiotics

On the difference between bacteriostatic and bactericidal antibiotics
The difference between male bacteriostatic and bactericidal antibiotics must be investigated by doctors. Although both are tools for bacteriotics, their mechanisms of action and efficacy are different, which cannot be ignored.

Bacteriostatic antibiotics can inhibit the rate of bacterial reproduction and prevent their division and proliferation, but not directly kill them. They act on the metabolic process of bacteria, or interfere with their protein synthesis, or hinder their nucleic acid production. Such as tetracyclines, they can bind to the bacterial ribosome and prevent the binding of aminoyl-tRNA to the A position of the ribosome, thereby inhibiting protein synthesis and stagnating bacterial growth and reproduction. In this situation, although the bacteria do not die immediately, their vitality is greatly reduced, and the body's immune function has to multiply and overcome them. If the body's immunity is normal, bacteriostatic drugs can often work; if the immunity is weak, it will be difficult to achieve full effect, and the bacteria may relapse and become ill again.

Bactericidal antibiotics are not the same, which can directly break the structure of the bacteria, destroy their key physiological functions, and cause them to die quickly. For example, beta-lactams can inhibit the synthesis of the bacterial cell wall, cause the cell wall to be damaged, increase the osmotic pressure in the bacteria, and the bacteria will expand and lyse and die. Such antibiotics act rapidly on bacteria, and can kill a large number of bacteria without waiting for the immune help of the body. In the case of severe infections and immunocompromised infections, bactericidal antibiotics are often the first choice, which can quickly control the disease and save life in the dying.

Looking at the difference between the two, clinical medication must carefully review the disease, patient's physique, and bacterial characteristics. For mild diseases and good immunity, bacteriostatic drugs may be treatable, economical and less side effects; for severe, immunoweakened or life-threatening infections, bactericidal drugs should be urgently administered to quickly remove the pathogen and ensure the well-being of the patient. Doctors should study the difference between the two and use them rationally, which is the right way of medicine and the gospel of patients.