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Coagulase Role in Pathogenicity
"On the Benefits of Coagulase in Pathogenicity"
The husband of coagulase, on the way to pathogenesis, is the culprit. Watching the disease bacteria often rely on many tricks, and coagulase is one of its main tools.
Coagulase can convert fibrinogen in plasma into fibrin, and this change is wonderful, like building a barrier. Around the bacteria, fibrin coagulates into a block, which is like a solid wall, and the bacteria hide in it, which can avoid the sharp defense of the host. Immune cells want to suppress the bacteria, but when they encounter this barrier, it is difficult to enter, so that the bacteria can be safe.
The coagulation promoted by coagulase can change the microenvironment of the bacteria. The change of micro-environment is beneficial to the survival and reproduction of pathogens. For example, nutrient transportation can be exclusive to pathogens due to the coagulation structure, resulting in more vigorous growth.
Furthermore, the coagulation phenomenon caused by coagulase can interfere with the normal physiological order of the host. At the site of coagulation, physiological function is blocked, and the health of the host is threatened. Bacteria use the power of coagulase to expand their power in the host, which is the foundation for pathogenesis. From this point of view, coagulase plays a pivotal role in the pathogenicity of pathogens and helps pathogens.
The husband of coagulase, on the way to pathogenesis, is the culprit. Watching the disease bacteria often rely on many tricks, and coagulase is one of its main tools.
Coagulase can convert fibrinogen in plasma into fibrin, and this change is wonderful, like building a barrier. Around the bacteria, fibrin coagulates into a block, which is like a solid wall, and the bacteria hide in it, which can avoid the sharp defense of the host. Immune cells want to suppress the bacteria, but when they encounter this barrier, it is difficult to enter, so that the bacteria can be safe.
The coagulation promoted by coagulase can change the microenvironment of the bacteria. The change of micro-environment is beneficial to the survival and reproduction of pathogens. For example, nutrient transportation can be exclusive to pathogens due to the coagulation structure, resulting in more vigorous growth.
Furthermore, the coagulation phenomenon caused by coagulase can interfere with the normal physiological order of the host. At the site of coagulation, physiological function is blocked, and the health of the host is threatened. Bacteria use the power of coagulase to expand their power in the host, which is the foundation for pathogenesis. From this point of view, coagulase plays a pivotal role in the pathogenicity of pathogens and helps pathogens.
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